产品详情
产品名称DISP1 Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB
种属反应性Human
免疫原描述Recombinant fusion protein of human DISP1 (NP_116279.2).
标记Unconjugated
别名DISP1; DISPA; protein dispatched homolog 1
数据库入口号Swiss-Prot#:Q96F81
NCBI Gene ID:84976
Uniprot
Q96F81
计算分子量180kDa
配方Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
保存Store at -20˚C
应用详情
WB 1:500 - 1:2000
Western blot analysis of extracts of various cell lines, using DISP1 antibody.
The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo.
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et al,MAPK1 regulates platelet function and thrombus formation
, (2025),
PMID:
40447106
Yes
