产品详情
产品名称TIMM44 Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IF
种属反应性Human;Mouse;Rat
免疫原描述Recombinant fusion protein of human TIMM44 (NP_006342.2).
标记Unconjugated
别名TIM44
数据库入口号Swiss-Prot#:O43615
NCBI Gene ID:10469
Uniprot
O43615
计算分子量51kDa
配方Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
保存Store at -20˚C
应用详情
WB 1:500 - 1:2000
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using TIMM44 antibody at 1:1000 dilution.
Immunofluorescence analysis of L929 cells using TIMM44 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U-2 OS cells using TIMM44 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
This gene encodes a peripheral membrane protein associated with the mitochondrial inner membrane translocase, which functions in the import of proteins across the mitochondrial inner membrane and into the mitochondrial matrix. The encoded protein mediates binding of mitochondrial heat shock protein 70 to the translocase of inner mitochondrial membrane 23 (TIM23) complex. Expression of this gene is upregulated in kidney in a mouse model of diabetes. A mutation in this gene is associated with familial oncocytic thyroid carcinoma.
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et al,Anticancer, Anti‐Inflammatory, and Acute Toxicological Evaluation of the Novel Berberine Derivative BN‐7
, (2025),
PMID:
41417275
Yes
