产品详情
产品名称LEPREL1 Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB
种属反应性Human;Mouse;Rat
免疫原描述Recombinant fusion protein of human LEPREL1 (NP_060662.2).
标记Unconjugated
别名P3H2; LEPREL1; MCVD; MLAT4; prolyl 3-hydroxylase 2
数据库入口号Swiss-Prot#:Q8IVL5
NCBI Gene ID:55214
Uniprot
Q8IVL5
计算分子量85kDa
配方Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
保存Store at -20˚C
应用详情
WB 1:500 - 1:2000
Western blot analysis of extracts of NCI-H460 cells, using LEPREL1 antibody.
This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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, (2025),
PMID:
40992491
Yes
