产品详情
产品名称A2M Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total A2M protein.
免疫原类型Peptide
免疫原描述Recombinant fusion protein of human Alpha-2-Macroglobulin (Alpha-2-Macroglobulin (A2M)) (NP_000005.2).
基因/蛋白名称A2M
标记Unconjugated
别名A2M;A2MD;CPAMD5;FWP007;S863-7
数据库入口号Uniprot:P01023
GeneID:2
Uniprot
P01023
Gene ID
2
实际分子量160kDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
Western blot analysis of extracts of various cell lines, using Alpha-2-Macroglobulin (Alpha-2-Macroglobulin (A2M)) antibody.
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
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et al,LncRNA ZFAS1 Combined with SRSF1 Regulate CNPY2 Expression and Leads to Microglia Endoplasmic Reticulum Stress–Induced Spinal Cord Injury
, (2025),
PMID:
40465066
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