产品详情
产品名称PTGR1 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
应用WB
种属反应性Human
特异性The antibody detects endogenous levels of total PTGR1 protein.
免疫原类型Peptide
免疫原描述Synthesized peptide derived from internal of human PTGR1.
基因/蛋白名称PTGR1
标记Unconjugated
别名Prostaglandin reductase 1; PRG-1; NADP-dependent leukotriene B4 12-hydroxydehydrogenase; EC=1.3.1.74; 15-oxoprostaglandin 13-reductase
数据库入口号Swiss-Prot: Q14914
NCBI Gene ID: 22949
Uniprot
Q14914
实际分子量36kd
浓度1.0mg/ml
配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500~1:3000
Western blot analysis of extracts from HT-29 cells, using PTGR1 antibody #34841.
Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha By similarity. Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4.
Humphray S.J., Nature 429:369-374(2004).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Yokomizo T., J. Biol. Chem. 271:2844-2850(1996)
如果您使用该产品34841发表了文章，请通知我们，让我们可以引用您的文献。
et al,analysis: an analysis based on the European spontaneous adverse event reporting system
, (2025),
PMID:
39877384
有货
