产品详情
产品名称SIRT3 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
应用WB
种属反应性Human
特异性The antibody detects endogenous levels of total SIRT3 protein.
免疫原类型Peptide
免疫原描述Synthesized peptide derived from C-terminal of human SIRT3.
基因/蛋白名称SIRT3
标记Unconjugated
别名NAD-dependent deacetylase sirtuin-3; mitochondrial; SIR2-like protein 3; hSIRT3; SIRT3
数据库入口号Swiss-Prot: Q9NTG7
NCBI Gene ID: 23410
Uniprot
Q9NTG7
实际分子量45kd
浓度1.0mg/ml
配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500~1:3000
Western blot analysis of extracts from COLO205 cells, using SIRT3 antibody #35202.
NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.
Bechtel S., BMC Genomics 8:399-399(2007).
Schwer B., J. Cell Biol. 158:647-657(2002).
Onyango P., Proc. Natl. Acad. Sci. U.S.A. 99:13653-13658(2002).
如果您使用该产品35202发表了文章，请通知我们，让我们可以引用您的文献。
et al,Dendrobium officinale polysaccharide inhibits M1 macrophage polarization via activating SENP1-SIRT3 signaling and alleviates ulcerative colitis
, (2025),
PMID:
41185333
有货
