产品详情
产品名称AKR1B10 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human
特异性The antibody detects endogenous levels of total AKR1B10 protein.
免疫原类型Recombinant Protein
免疫原描述Full length fusion protein
基因/蛋白名称AKR1B10
标记Unconjugated
别名HIS; HSI; ARL1; ARL-1; ALDRLn; AKR1B11; AKR1B12
数据库入口号Swiss-Prot#: O60218
NCBI Gene ID: 57016
Gene Accssion: BC008837
Uniprot
O60218
实际分子量36kd
浓度0.7mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
Gel: 10%SDS-PAGE
Lysates (from left to right): Raji and Jurkat cell
Amount of lysate: 40ug per lane
Primary antibody: 1/175 dilution
Secondary antibody dilution: 1/8000
Exposure time: 10 seconds
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #36071 at dilution 1/20.
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis.
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et al,AKR1B10 dictates c-Myc stability to suppress colorectal cancer metastasis via PP2A nitration
, (2025),
PMID:
40845116
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