产品详情
产品名称ANAPC4 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human;Mouse
特异性The antibody detects endogenous levels of total ANAPC4 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to a region derived from internal residues of human anaphase promoting complex subunit 4
基因/蛋白名称ANAPC4
标记Unconjugated
别名APC4
数据库入口号Swiss-Prot#: Q9UJX5
NCBI Gene ID: 29945
Gene Accssion: NP_037499
Uniprot
Q9UJX5
实际分子量92kd
浓度2.6mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200
Gel: 6%SDS-PAGE
Lysates (from left to right): HepG2, 231 and hela cell
Amount of lysate: 40ug per lane
Primary antibody: 1/300 dilution
Secondary antibody dilution: 1/8000
Exposure time: 1 minute
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #37110 at dilution 1/50.
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans.?
如果您使用该产品37110发表了文章，请通知我们，让我们可以引用您的文献。
et al,Hybrid-Ligand Metal–Organic Frameworks Enabling Radio–Radiodynamic–Chemodynamic Therapy Primes Checkpoint Blockade Immunotherapy in Hypoxic Tumors
, (2025),
PMID:
40802503
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