产品详情
产品名称ABCC9 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous levels of total ABCC9 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to residues near the C terminal of human ATP-binding cassette, sub-family C (CFTR/MRP), member 9
基因/蛋白名称ABCC9
标记Unconjugated
别名SUR2; ABC37; CANTU; CMD1O; ATFB12
数据库入口号Swiss-Prot:O60706
Gene Accssion:NP_005682
Uniprot
O60706
实际分子量175KD
浓度1.1mg/ml
配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:100-1:200
Gel: 6%SDS-PAGE
Lysate: 40ug Mouse bladder tissuePrimary antibody: 1/300 dilution
Secondary antibody dilution: 1/8000
Exposure time: 5 minutes
Immunohistochemical analysis of paraffin-embedded Human Liver cancer tissue using #40229 at dilution 1/100.
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle.?
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et al,ABCC9 knockdown attenuates isoproterenol-induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway
, (2025),
PMID:
41347799
Yes
