产品详情
产品名称RGN Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification
应用WB
种属反应性Human;Mouse
特异性The antibody detects endogenous levels of total RGN protein.
免疫原类型peptide
免疫原描述Synthetic peptide corresponding to residues near the C terminal of human RGN
基因/蛋白名称RGN
标记Unconjugated
别名RC; GNL; SMP30; HEL-S-41
数据库入口号Swiss-Prot:Q15493
NCBI Gene ID:9104
NCBI Protein:NP_004674
Uniprot
Q15493
计算分子量33 kDa
浓度1mg/ml
配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500-1:2000
Gel: 8%SDS-PAGE
lysate: 40 ¦Ìg, Lane 1-2: Mouse liver tissue and Human fetal liver tissue lysates,
Primary antibody: 46660£¨RGN Antibody) at dilution 1/500
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,
Exposure time: 20 seconds
The protein encoded by this gene is a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and kidney. It may have an important role in calcium homeostasis. Studies in rat indicate that this protein may also play a role in aging, as it shows age-associated down-regulation. This gene is part of a gene cluster on chromosome Xp11.3-Xp11.23. Alternative splicing results in multiple transcript variants.
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et al,Nucleus-translocated glucokinase functions as a protein kinase to phosphorylate TAZ and promote tumour growth
, (2025),
PMID:
40759645
Yes
