产品详情
产品名称LCN2 Rabbit Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IF
种属反应性Human;Mouse;Rat
免疫原描述Recombinant protein of human LCN2
标记Unconjugated
别名LCN2;24p3;MSFI;NGAL;p25
数据库入口号Swiss Prot:P80188
GeneID:3934
Uniprot
P80188
计算分子量22kDa
实际分子量23kDa
配方Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IF 1:10 - 1:100
Immunofluorescence analysis of A-549 cells using LCN2 . Blue: DAPI for nuclear staining.
Western blot analysis of extracts of A-549 cells, using LCN2 at 1:1000 dilution.
This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice.
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et al,HSP47 inhibitor Col003 may attenuates neurological impairment in chronic ischemic stroke rats by inhibiting LCN2
, (2025),
PMID:
41185942
Yes
