产品详情
产品名称Slug Rabbit Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC
种属反应性Human;Mouse;Rat
免疫原描述Recombinant fusion protein of human Slug (NP_003059.1).
标记Unconjugated
别名SNAI2;SLUG;SLUGH;SLUGH1;SNAIL2;WS2D
数据库入口号Swiss Prot:O43623
GeneID:6591
Uniprot
O43623
计算分子量29kDa
配方Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:2000 - 1:5000
IHC 1:50 - 1:200
Immunohistochemistry of paraffin-embedded human liver damage using Slug at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human breast cancer using Slug at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human stomach using Slug at dilution of 1:100 (40x lens).
This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.
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et al,FGL1-mediated lymph node metastasis in stage T1 non-small cell lung cancer: therapeutic targeting
, (2025),
PMID:
41024301
Yes
