产品详情
产品名称Snail Rabbit Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC,IF
种属反应性Human;Mouse;Rat
免疫原描述A synthetic peptide of human Snail (NP_005976.2).
标记Unconjugated
别名SNAI1;SLUGH2;SNA;SNAH;SNAIL;SNAIL1;dJ710H13.1
数据库入口号Swiss Prot:O95863
GeneID:6615
Uniprot
O95863
计算分子量29kDa
实际分子量29kDa
配方Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using Snail at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded human breast using Snail at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human colon using Snail at dilution of 1:100 (40x lens).
Immunofluorescence analysis of C6 cells using Snail at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U-2 OS cells using Snail at dilution of 1:100. Blue: DAPI for nuclear staining.
The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2.
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et al,FGL1-mediated lymph node metastasis in stage T1 non-small cell lung cancer: therapeutic targeting
, (2025),
PMID:
41024301